Title : TNF-α mediates PKCδ/JNK1/2/c-Jun-dependent monocyte adhesion via ICAM-1 induction in human retinal pigment epithelial cells.

Pub. Date : 2015

PMID : 25675437






1 Functional Relationships(s)
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1 TNF-alpha-mediated responses were attenuated by pretreatment with the inhibitor of PKCs (Ro318220), PKCdelta (Rottlerin), MEK1/2 (U0126), JNK1/2 (SP600125), or AP-1 (Tanshinone IIA) and transfection with siRNA of TNFR1, TRAF2, JNK2, p42, or c-Jun. U 0126 tumor necrosis factor Homo sapiens