Title : Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation.

Pub. Date : 2015 Apr 9

PMID : 25673640






1 Functional Relationships(s)
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1 In this study, we demonstrate that immune suppression with cyclosporin after SCT limits T-helper cell (Th) 1 differentiation and interferon-gamma secretion by donor T cells, which is critical for inhibiting interleukin (IL)-6 generation from lung parenchyma during an alloimmune response. Cyclosporine interferon gamma Homo sapiens