Title : p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor.

Pub. Date : 1989 Mar

PMID : 2566907






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We show here that a monoclonal antibody directed against the extracellular domain of p185HER2 specifically inhibits the growth of breast tumor-derived cell lines overexpressing the HER2/c-erbB-2 gene product and prevents HER2/c-erbB-2-transformed NIH 3T3 cells from forming colonies in soft agar. Agar erb-b2 receptor tyrosine kinase 2 Mus musculus
2 We show here that a monoclonal antibody directed against the extracellular domain of p185HER2 specifically inhibits the growth of breast tumor-derived cell lines overexpressing the HER2/c-erbB-2 gene product and prevents HER2/c-erbB-2-transformed NIH 3T3 cells from forming colonies in soft agar. Agar erb-b2 receptor tyrosine kinase 2 Mus musculus