Title : Curcumin binds to the pre-fibrillar aggregates of Cu/Zn superoxide dismutase (SOD1) and alters its amyloidogenic pathway resulting in reduced cytotoxicity.

Pub. Date : 2015 May

PMID : 25666897






2 Functional Relationships(s)
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1 In the present study, we observed the fibrillation of one of the premature forms of SOD1 (SOD1 with reduced disulfide) in the presence of curcumin. Disulfides superoxide dismutase 1 Homo sapiens
2 In the present study, we observed the fibrillation of one of the premature forms of SOD1 (SOD1 with reduced disulfide) in the presence of curcumin. Disulfides superoxide dismutase 1 Homo sapiens