Title : Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation.

Pub. Date : 2015 Feb 10

PMID : 25665524






1 Functional Relationships(s)
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1 Importantly, the FDA-approved drug celecoxib re-establishes the AKT/miR-199a-5p/CAV1 axis in CF macrophages, and ameliorates lung hyper-inflammation in Cftr-deficient mice. Celecoxib thymoma viral proto-oncogene 1 Mus musculus