Title : MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways.

Pub. Date : 2015 Feb 7

PMID : 25663768






1 Functional Relationships(s)
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1 In addition, pre-miR-21-LV or siRASA1 (down-regulation of RASA1) cells showed higher cell proliferation, reduced apoptosis, increased expression of RAS-GTP, p-AKT, Raf-1, KRAS, and p-ERK1/2, and higher invasion and tumor formation ability, compared with control, anti-miR-21-LV or pcDNA3.1-RASA1 (up-regulation of RASA1) cells (P < 0.05). Radium mitogen-activated protein kinase 3 Homo sapiens