Pub. Date : 2015 Mar 15
PMID : 25662586
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the current study, we determined the effects of the PPAR-beta/delta agonist GW0742 on HDL composition and the expression of liver HDL-related genes in mice and cultured human cells. | GW0742 | peroxisome proliferator activator receptor delta | Mus musculus |
| 2 | The GW0742-mediated effects on liver Pltp expression and serum enzyme activity were completely abolished in PPAR-beta/delta-deficient mice. | GW0742 | peroxisome proliferator activator receptor delta | Mus musculus |
| 3 | Collectively, our findings demonstrate a common transcriptional upregulation by GW0742-activated PPAR-beta/delta of Pltp expression in cultured cells and in mouse liver resulting in enhanced serum PLTP activity. | GW0742 | peroxisome proliferator activator receptor delta | Mus musculus |