Title : Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia.

Pub. Date : 2015 Apr

PMID : 25661249






4 Functional Relationships(s)
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1 Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia. Diltiazem angiotensinogen Rattus norvegicus
2 Our study showed that AngII and hypoxia decreased the mitochondrial membrane potential in VEC, which was significantly inhibited by diltiazem. Diltiazem angiotensinogen Rattus norvegicus
3 Diltiazem protected against VEC injury induced by the increased concentration of intracellular free calcium, which was associated with AngII and hypoxia. Diltiazem angiotensinogen Rattus norvegicus
4 Diltiazem, a calcium channel blocker, protected VEC from AngII- and hypoxia-induced injury. Diltiazem angiotensinogen Rattus norvegicus