Title : Safety of valproic acid in patients with chronic obstructive pulmonary disease: a population-based cohort study.

Pub. Date : 2015 Mar

PMID : 25656984






3 Functional Relationships(s)
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1 PURPOSE: Valproic acid is an anticonvulsant that also inhibits histone deacetylase (HDAC), a property that could worsen pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Valproic Acid histone deacetylase 9 Homo sapiens
2 PURPOSE: Valproic acid is an anticonvulsant that also inhibits histone deacetylase (HDAC), a property that could worsen pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Valproic Acid histone deacetylase 9 Homo sapiens
3 These findings suggest that valproate-induced HDAC inhibition is of little clinical relevance in this context. Valproic Acid histone deacetylase 9 Homo sapiens