Title : Mitochondrial DNA oxidative damage contributes to cardiomyocyte ischemia/reperfusion-injury in rats: cardioprotective role of lycopene.

Pub. Date : 2015 Sep

PMID : 25656550






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 I/R-injury decreased the protein level of a key activator of mt transcription, mitochondrial transcription factor A (Tfam), which was blocked by lycopene. Lycopene transcription factor A, mitochondrial Rattus norvegicus
2 The protective effect of lycopene on mtDNA was associated with a reduction in mitochondrial ROS production and stabilization of Tfam. Lycopene transcription factor A, mitochondrial Rattus norvegicus