Pub. Date : 2015 Jan
PMID : 25655724
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of the Trio-mediated Rac1 guanine nucleotide exchange activity with ITX3 partially blocked the SV4-mediated increase in Rac1-GTP. | Guanine Nucleotides | Rac family small GTPase 1 | Homo sapiens |
| 2 | Inhibition of the Trio-mediated Rac1 guanine nucleotide exchange activity with ITX3 partially blocked the SV4-mediated increase in Rac1-GTP. | Guanine Nucleotides | Rac family small GTPase 1 | Homo sapiens |
| 3 | Supervillin and Trio knockdowns, separately or together, inhibited cell spreading, suggesting that supervillin regulates the Rac1 guanine nucleotide exchange activity of Trio, and potentially also kalirin, during cell spreading and lamellipodia extension. | Guanine Nucleotides | Rac family small GTPase 1 | Homo sapiens |