Pub. Date : 1989
PMID : 2565539
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mean NAG value corrected for creatinine in the higher cadmium group (2.95 U/g creatinine) is significantly different from the mean low cadmium group value (0.92 U/g creatinine, p = 0.0083). | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 2 | NAG and AAP also give significant correlations with cadmium levels in urine (NAG: r = 0.51; p = 0.0001; AAP: r = 0.56; p = 0.0001). | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 3 | NAG and AAP also give significant correlations with cadmium levels in urine (NAG: r = 0.51; p = 0.0001; AAP: r = 0.56; p = 0.0001). | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 4 | A dose-response relationship was found between NAG and cadmium and between AAP and cadmium. | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 5 | A dose-response relationship was found between NAG and cadmium and between AAP and cadmium. | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 6 | The analysis of this relationship gives estimates of a 10% chance of observing an elevated NAG value at a cadmium level of 6.3 micrograms/g creatinine (8.0 micrograms/l) and a 10% chance of observing an elevated AAP at a cadmium level of 5.0 micrograms/g creatinine (3.4 micrograms/l). | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 7 | These data indicate elevations of NAG and AAP at urine cadmium levels below the level of 10 micrograms/g creatinine recommended as an upper limit by the 1980 World Health Organization Study Group. | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 8 | Since elevated levels of NAG and AAP in cadmium-exposed workers may reflect chronic renal tubular nephrotoxicity, these findings indicate that cadmium levels below 10 micrograms/g creatinine may be accompanied by subclinical tubular dysfunction, and that WHO guidelines should be interpreted cautiously, particularly with reference to workers who are no longer exposed and may have had higher cadmium body burdens in the past. | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 9 | Since elevated levels of NAG and AAP in cadmium-exposed workers may reflect chronic renal tubular nephrotoxicity, these findings indicate that cadmium levels below 10 micrograms/g creatinine may be accompanied by subclinical tubular dysfunction, and that WHO guidelines should be interpreted cautiously, particularly with reference to workers who are no longer exposed and may have had higher cadmium body burdens in the past. | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |
| 10 | Since elevated levels of NAG and AAP in cadmium-exposed workers may reflect chronic renal tubular nephrotoxicity, these findings indicate that cadmium levels below 10 micrograms/g creatinine may be accompanied by subclinical tubular dysfunction, and that WHO guidelines should be interpreted cautiously, particularly with reference to workers who are no longer exposed and may have had higher cadmium body burdens in the past. | Cadmium | N-acetyl-alpha-glucosaminidase | Homo sapiens |