Pub. Date : 2015 May
PMID : 25655388
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |
| 2 | In cells transfected with any of the three ornithine decarboxylase antizymes (AZ1, AZ2 and AZ3), agmatine uptake was dramatically reduced. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |
| 3 | Furthermore, whereas putrescine uptake was significantly decreased in cells transfected with ornithine decarboxylase (ODC), the accumulation of agmatine was stimulated, suggesting a trans-activating effect of intracellular putrescine on agmatine uptake. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |
| 4 | Furthermore, whereas putrescine uptake was significantly decreased in cells transfected with ornithine decarboxylase (ODC), the accumulation of agmatine was stimulated, suggesting a trans-activating effect of intracellular putrescine on agmatine uptake. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |
| 5 | Furthermore, whereas putrescine uptake was significantly decreased in cells transfected with ornithine decarboxylase (ODC), the accumulation of agmatine was stimulated, suggesting a trans-activating effect of intracellular putrescine on agmatine uptake. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |
| 6 | Furthermore, whereas putrescine uptake was significantly decreased in cells transfected with ornithine decarboxylase (ODC), the accumulation of agmatine was stimulated, suggesting a trans-activating effect of intracellular putrescine on agmatine uptake. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |
| 7 | All these results indicate that ODC and its regulatory proteins (antizymes and antizyme inhibitors) may influence agmatine homeostasis in mammalian tissues. | Agmatine | ornithine decarboxylase 1 | Homo sapiens |