Pub. Date : 2015 Jul
PMID : 25652250
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | CYP2B can metabolize nicotine, the main psychoactive ingredient in cigarettes; if altered brain CYP2B activity can influence nicotine brain levels, it could influence nicotine-mediated behaviors. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 4 | CYP2B can metabolize nicotine, the main psychoactive ingredient in cigarettes; if altered brain CYP2B activity can influence nicotine brain levels, it could influence nicotine-mediated behaviors. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 5 | CYP2B can metabolize nicotine, the main psychoactive ingredient in cigarettes; if altered brain CYP2B activity can influence nicotine brain levels, it could influence nicotine-mediated behaviors. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 6 | CYP2B can metabolize nicotine, the main psychoactive ingredient in cigarettes; if altered brain CYP2B activity can influence nicotine brain levels, it could influence nicotine-mediated behaviors. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 7 | CYP2B can metabolize nicotine, the main psychoactive ingredient in cigarettes; if altered brain CYP2B activity can influence nicotine brain levels, it could influence nicotine-mediated behaviors. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 8 | CYP2B can metabolize nicotine, the main psychoactive ingredient in cigarettes; if altered brain CYP2B activity can influence nicotine brain levels, it could influence nicotine-mediated behaviors. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 9 | Together these data demonstrate that the brain CYP2B activity can influence nicotine brain levels and subsequent behaviors independent of hepatic metabolism. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 10 | This suggests that human smokers with variable CYP2B brain levels could have different nicotine levels and reinforcement, which might have a role in smoking behaviors and dependence. | Nicotine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |