Title : Acetylcholinesterase conformational states influence nitric oxide mobilization in the erythrocyte.

Pub. Date : 2015 Apr

PMID : 25652185






2 Functional Relationships(s)
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1 In addition, the present study shows evidence that conformational changes in AChE promoted by incubation with N-19 and C-16 antibodies alter the enzyme"s functional connection to acetylcholine (ACh) (AChE-ACh complex) in an irreversible manner, resulting in impaired GSNO concentration and NO efflux from the erythrocyte. S-Nitrosoglutathione acetylcholinesterase (Cartwright blood group) Homo sapiens
2 In addition, the present study shows evidence that conformational changes in AChE promoted by incubation with N-19 and C-16 antibodies alter the enzyme"s functional connection to acetylcholine (ACh) (AChE-ACh complex) in an irreversible manner, resulting in impaired GSNO concentration and NO efflux from the erythrocyte. S-Nitrosoglutathione acetylcholinesterase (Cartwright blood group) Homo sapiens