Pub. Date : 2015 May 1
PMID : 25651569
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated the role of soluble uric acid in NLRP3 inflammasome activation in macrophages to demonstrate the effect of systemic hyperuricemia on progressive kidney damage in type 2 diabetes. | Uric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Soluble uric acid stimulated NLRP3 inflammasomes to produce IL-1beta in macrophages. | Uric Acid | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Uric acid-induced MitoSOX mediates NLRP3 activation and IL-1beta secretion. | Uric Acid | NLR family pyrin domain containing 3 | Homo sapiens |