Pub. Date : 2015 May
PMID : 25649051
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | BACKGROUND AND PURPOSE: Opicapone (OPC) is a novel third generation catechol-O-methyltransferase (COMT) inhibitor that enhances levodopa availability. | Levodopa | catechol-O-methyltransferase | Homo sapiens |
2 | BACKGROUND AND PURPOSE: Opicapone (OPC) is a novel third generation catechol-O-methyltransferase (COMT) inhibitor that enhances levodopa availability. | Levodopa | catechol-O-methyltransferase | Homo sapiens |
3 | CONCLUSIONS: OPC is a promising new COMT inhibitor that significantly decreased COMT activity, increased systemic exposure to levodopa and improved motor response. | Levodopa | catechol-O-methyltransferase | Homo sapiens |