Title : L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.

Pub. Date : 2015 Feb

PMID : 25644346






2 Functional Relationships(s)
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1 Silencing betaine homocysteine methyltransferase, cystathionine beta-synthase, or methionine increased intracellular homocysteine and TG concentrations by >2-fold, which was reversed by L-serine when L-serine-independent betaine homocysteine methyltransferase was knocked down. Serine cystathionine beta-synthase Mus musculus
2 Silencing betaine homocysteine methyltransferase, cystathionine beta-synthase, or methionine increased intracellular homocysteine and TG concentrations by >2-fold, which was reversed by L-serine when L-serine-independent betaine homocysteine methyltransferase was knocked down. Serine cystathionine beta-synthase Mus musculus