Title : Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.

Pub. Date : 2015 Jun 5

PMID : 25641190






1 Functional Relationships(s)
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1 Two of the aromatic lactones show selectivity within the ALDH1/2 class, and one appears to be selective for ALDH2 compared to all other isoenzymes tested. Lactones aldehyde dehydrogenase 2 family member Homo sapiens