Title : Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.

Pub. Date : 2015 Jan 30

PMID : 25635101






1 Functional Relationships(s)
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1 We report crystal structures (at 1.8, 2.4, and 2.5 angstrom resolution) of TSPO from Rhodobacter sphaeroides and a mutant that mimics the human Ala(147) Thr(147) polymorphism associated with psychiatric disorders and reduced pregnenolone production. Pregnenolone translocator protein Homo sapiens