Title : Characterization of zofenoprilat as an inducer of functional angiogenesis through increased H2 S availability.

Pub. Date : 2015 Jun

PMID : 25631232






2 Functional Relationships(s)
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1 The molecular mechanisms underlying H2 S/zofenoprilat-induced angiogenesis were dependent on Akt, eNOS and ERK1/2 cascades. Hydrogen Sulfide nitric oxide synthase 3 Homo sapiens
2 CONCLUSIONS AND IMPLICATIONS: Zofenoprilat induced a constant production of H2 S that stimulated the angiogenic process through a KATP channel/Akt/eNOS/ERK1/2 pathway. Hydrogen Sulfide nitric oxide synthase 3 Homo sapiens