Title : Conjugation of PolyPEG to interferon alpha extends serum half-life while maintaining low viscosity of the conjugate.

Pub. Date : 2015 Mar 18

PMID : 25629733






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Interferon-alpha (IFN) was conjugated via its N-terminal amino group by reductive amination to alpha-aldehyde functional comb-shaped PolyPEG polymers (50 and 70 kDa) and to linear PEG (30 kDa). alpha-aldehyde interferon alpha 1 Homo sapiens