Pub. Date : 2015 Jan 27
PMID : 25622857
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Consistently, higher expression of VEGF, MCP-1 and NF-kappaB was observed in HCC tissues of alcohol-drinkers. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | Conversely, blockage of alcohol-mediated ROS accumulation and NF-kappaB signaling inhibited alcohol-induced expression of VEGF and MCP-1, the tumor growth, angiogenesis and metastasis. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | Conversely, blockage of alcohol-mediated ROS accumulation and NF-kappaB signaling inhibited alcohol-induced expression of VEGF and MCP-1, the tumor growth, angiogenesis and metastasis. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | CONCLUSION: This study suggested that chronic moderate alcohol consumption may promote the progression and metastasis of HCC; the oncogenic effect may be at least partially mediated by the ROS accumulation and NF-kB-dependent VEGF and MCP-1 up-regulation. | Alcohols | C-C motif chemokine ligand 2 | Homo sapiens |