Title : Reversal effect of bufalin on multidrug resistance in K562/VCR vincristine-resistant leukemia cell line.

Pub. Date : 2014 Dec

PMID : 25618972






1 Functional Relationships(s)
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1 Preincubation of 0.001 mumol/L bufalin for 2 h could increase intracellular ADM fluorescence intensity to 28.07% (P < 0.05) and down-regulate MRP1 expression simultaneously, but no remarkable effect was found on P-gp protein. bufalin ATP binding cassette subfamily B member 1 Homo sapiens