Title : Tanshinone I induces cyclin D1 proteasomal degradation in an ERK1/2 dependent way in human colorectal cancer cells.

Pub. Date : 2015 Mar

PMID : 25615593






1 Functional Relationships(s)
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1 From these results, we suggest that TAN I-mediated cyclin D1 downregulation may result from proteasomal degradation through its ERK1/2-mediated phosphorylation of threonine-286. Threonine mitogen-activated protein kinase 3 Homo sapiens