Title : Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.

Pub. Date : 2015 Feb 15

PMID : 25609843






3 Functional Relationships(s)
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1 Knockdown of the constitutively expressed DNA sensor DDX41 attenuates poly(dA:dT)-triggered IFN-beta production and cGAS induction. amsonic acid interferon beta 1 Homo sapiens
2 By analyzing the dynamic expression of poly(dA:dT)-induced IFN-beta and cGAS transcripts, we have found that induction of IFN-beta is earlier than cGAS. amsonic acid interferon beta 1 Homo sapiens
3 By analyzing the dynamic expression of poly(dA:dT)-induced IFN-beta and cGAS transcripts, we have found that induction of IFN-beta is earlier than cGAS. amsonic acid interferon beta 1 Homo sapiens