Title : Regulation of Transforming Growth Factor β1, Platelet-Derived Growth Factor, and Basic Fibroblast Growth Factor by Silicone Gel Sheeting in Early-Stage Scarring.

Pub. Date : 2015 Jan

PMID : 25606485






3 Functional Relationships(s)
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1 Regulation of Transforming Growth Factor beta1, Platelet-Derived Growth Factor, and Basic Fibroblast Growth Factor by Silicone Gel Sheeting in Early-Stage Scarring. Silicones fibroblast growth factor 2 Homo sapiens
2 The expression of bFGF in the dermis was significantly higher in the case of silicone gel sheet-treated scars than in the case of untreated scars (P=0.042), but in the epidermis, the expression of bFGF showed no significant difference between the groups (P=0.655). Silicones fibroblast growth factor 2 Homo sapiens
3 CONCLUSIONS: The levels of TGF-beta1, PDGF, and bFGF are altered by the silicone gel sheet treatment, which might be one of the mechanisms of action in scar prevention. Silicones fibroblast growth factor 2 Homo sapiens