Pub. Date : 2015 Feb 23
PMID : 25604474
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | With the aim to design new biologically active bioinorganic drugs of aspirin, whose mode of action is based on the inhibition of the cyclooxygenase(COX) enzymes, derivatives of Zeise"s salt were synthesized in this structure-activity relationship study. | Aspirin | cytochrome c oxidase subunit 8A | Homo sapiens |
| 2 | Surprisingly, not only these Zeise-aspirin compounds but also Zeise"s salt itself showed high inhibitory potency against COX enzymes in in vitro assays. | Aspirin | cytochrome c oxidase subunit 8A | Homo sapiens |