Title : Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression.

Pub. Date : 2016 Feb

PMID : 25604428






2 Functional Relationships(s)
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1 It has been suggested that the irreversible MAO-B inhibitors selegiline and rasagiline exert a neuroprotective effect in Parkinson"s and Alzheimer"s diseases. rasagiline monoamine oxidase B Homo sapiens
2 There is increasing evidence that MAO-A activity, but not that of MAO-B, is implicated in the pathophysiology of neurodegenerative disorders, but also in gene induction by MAO-B inhibitors; on the other hand, selegiline and rasagiline increase MAO-A mRNA, protein, and enzyme activity levels. rasagiline monoamine oxidase B Homo sapiens