Pub. Date : 1989 Oct
PMID : 2559440
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxidation of diethyldithiocarbamate to disulfiram by liver microsomal cytochrome P-450-containing monooxygenase system. | Disulfiram | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | We examined the involvement of cytochrome P-450 in the oxidation of diethyldithiocarbamate (DTC) to disulfiram (DS) by liver microsomes in the presence of NADPH. | Disulfiram | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | We examined the involvement of cytochrome P-450 in the oxidation of diethyldithiocarbamate (DTC) to disulfiram (DS) by liver microsomes in the presence of NADPH. | Disulfiram | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 4 | It is concluded that oxidation of DTC to DS by liver microsomes largely proceeds via the cytochrome P-450-containing monooxygenase system and partly by hydrogen peroxide generated during NADPH oxidation. | Disulfiram | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |