Title : Overexpression of interleukin-18 protein reduces viability and induces apoptosis of tongue squamous cell carcinoma cells by activation of glycogen synthase kinase-3β signaling.

Pub. Date : 2015 Mar

PMID : 25591548






1 Functional Relationships(s)
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1 IL-18 expression upregulated the expression and phosphorylation of glycogen synthase kinase (GSK)-3beta protein in CRL1623 cells, whereas the selective GSK-3beta inhibitor kenpaullone antagonized the effects of IL-18 protein on TSCC cells in vitro. kenpaullone glycogen synthase kinase 3 beta Homo sapiens