Title : Oxidation of p53 through DNA charge transport involves a network of disulfides within the DNA-binding domain.

Pub. Date : 2015 Jan 27

PMID : 25584637






2 Functional Relationships(s)
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Protein Name
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1 Differential thiol labeling was used to determine the oxidation states of cysteine residues within p53 after DNA-mediated oxidation. Cysteine tumor protein p53 Homo sapiens
2 A distinct shift in peptide labeling toward (13)C2D2-iodoacetamide-labeled cysteines is observed in oxidized samples, confirming that chemical oxidation of p53 occurs at long range. Cysteine tumor protein p53 Homo sapiens