Title : PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers.

Pub. Date : 2015 Mar

PMID : 25582697






2 Functional Relationships(s)
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Protein Name
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1 Molecular analysis of lymphomas revealed that arginine methylation of p53 selectively suppresses expression of crucial proapoptotic and antiproliferative target genes, thereby sustaining tumor cell self-renewal and proliferation and bypassing the need for the acquisition of inactivating p53 mutations. Arginine tumor protein p53 Homo sapiens
2 Molecular analysis of lymphomas revealed that arginine methylation of p53 selectively suppresses expression of crucial proapoptotic and antiproliferative target genes, thereby sustaining tumor cell self-renewal and proliferation and bypassing the need for the acquisition of inactivating p53 mutations. Arginine tumor protein p53 Homo sapiens