Pub. Date : 2014 Nov
PMID : 25579023
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Compared with paraquat poisioning group, the pulmonary SOD, Nrf2 mRNA and protein were increased and the lung wet dry ratio were all significantly decreased in mice of THD treatment group at 1 d, 3 d, 7 d (P<0.05). | Paraquat | nuclear factor, erythroid derived 2, like 2 | Mus musculus |
| 2 | CONCLUSIONS: Lipid peroxide damage was one of the mechanisms of paraquat poisioning, thalidomide could attenuate paraquat-induced acute lung injury and its mechanism may be activating the Nrf2-ARE signaling pathway to protect mouse from Lipid peroxide damage. | Paraquat | nuclear factor, erythroid derived 2, like 2 | Mus musculus |