Title : Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.

Pub. Date : 2015 Apr

PMID : 25576397






1 Functional Relationships(s)
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1 The unique proline isomerase Pin1 is pivotal for protecting against age-dependent neurodegeneration in Alzheimer"s disease (AD), with its inhibition providing a molecular link between tangle and plaque pathologies. Proline peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens