Pub. Date : 2015
PMID : 25574848
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Low H2O2 dose (5microM) rapidly triggered a signaling cascade leading to nSMase2 activation, src and annexin 2 (AnxA2) phosphorylation, and actin remodeling, in fibroblasts and SMC. | Hydrogen Peroxide | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 2 | Finally we show that nSMase2 activation by H2O2, depends on MMP2 and p38MAPK, and is required for the src-dependent phosphorylation of AnxA2, and actin remodeling. | Hydrogen Peroxide | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |