Title : Novel target to kill CLL.

Pub. Date : 2015 Jan 8

PMID : 25573966






1 Functional Relationships(s)
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1 In this issue of Blood, Liu et al report on OSU-T315, a new agent that specifically disrupts the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway and shows high proapoptotic activity against chronic lymphocytic leukemia (CLL) cells, which may indicate a potential therapeutic application in this disease osu AKT serine/threonine kinase 1 Homo sapiens