Title : Haloperidol inhibits the development of atherosclerotic lesions in LDL receptor knockout mice.

Pub. Date : 2015 May

PMID : 25572138






2 Functional Relationships(s)
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1 KEY RESULTS: Haloperidol induced a 54% decrease in the mRNA expression of ABCA1 in peritoneal macrophages. Haloperidol ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus
2 Haloperidol treatment stimulated the expression of ABCA1 (+51%) and other genes involved in reverse cholesterol transport, that is, CYP7A1 (+98%) in livers of LDL receptor knockout mice. Haloperidol ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus