Pub. Date : 2014
PMID : 25571293
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Simvastatin, a commonly used HMG-CoA reductase inhibitor, is extensively metabolized by CYP3A4. | Simvastatin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | Therefore, co-administration of simvastatin and CYP3A4 inhibitor can affect simvastatin pharmacokinetics. | Simvastatin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |