Pub. Date : 2015 Feb
PMID : 25569743
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p21 activated kinase 1 (PAK1) mediates 5-ASA activity by orchestrating MAPK signaling, Wnt-beta catenin pathway, and cell adhesion; all implicated in the colon carcinogenesis. | Mesalamine | p21 (RAC1) activated kinase 1 | Homo sapiens |
| 2 | p21 activated kinase 1 (PAK1) mediates 5-ASA activity by orchestrating MAPK signaling, Wnt-beta catenin pathway, and cell adhesion; all implicated in the colon carcinogenesis. | Mesalamine | p21 (RAC1) activated kinase 1 | Homo sapiens |
| 3 | Moreover, 5-ASA disrupted PAK1 interaction and colocalization with beta-catenin. | Mesalamine | p21 (RAC1) activated kinase 1 | Homo sapiens |