Title : Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations.

Pub. Date : 2015 Feb 27

PMID : 25568328






2 Functional Relationships(s)
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1 The phenotypes of this panel of mutants were confirmed by imaging the RTX-evoked uptake of the large cationic fluorescent dye YO-PRO1. resiniferatoxin lamin A/C Homo sapiens
2 Whereas none of the mutations selectively altered capsaicin-induced changes in NMDG permeability, the loss-of-function phenotypes seen with RTX stimulation of G618W and M644I were recapitulated in the capsaicin-evoked YO-PRO1 uptake assay. resiniferatoxin lamin A/C Homo sapiens