Title : Role of the outer pore domain in transient receptor potential vanilloid 1 dynamic permeability to large cations.

Pub. Date : 2015 Feb 27

PMID : 25568328






2 Functional Relationships(s)
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1 Using resiniferatoxin (RTX) as the agonist, we identified multiple gain-of-function substitutions within the TRPV1 pore turret (N628P and S629A), pore helix (F638A), and selectivity filter (M644A) domains. resiniferatoxin transient receptor potential cation channel subfamily V member 1 Homo sapiens
2 Using resiniferatoxin (RTX) as the agonist, we identified multiple gain-of-function substitutions within the TRPV1 pore turret (N628P and S629A), pore helix (F638A), and selectivity filter (M644A) domains. resiniferatoxin transient receptor potential cation channel subfamily V member 1 Homo sapiens