Pub. Date : 2015 Feb 11
PMID : 25567764
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We report in this work that the Abeta peptide directly interacts with tubulin close to the vinblastine and GTP/GDP binding site, inhibits the tubulin polymerization rate, induces tubulin aggregation, causes cell shrinking, enhances Mad2, BubR1, p53, and p21 activation in MCF7 cells and induces the apoptotic death of A549, HeLa and MCF7 cells. | Guanosine Triphosphate | H3 histone pseudogene 16 | Homo sapiens |