Pub. Date : 2015
PMID : 25563368
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FOXM1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and mediates sensitivity to cisplatin in A549 cells via the JNK/mitochondrial pathway. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | Moreover, we showed that the downregulation of FoxM1 enhanced cisplatin-induced A549/CDDP cell apoptosis through the activation of the c-Jun NH2-terminal kinase (JNK)/mitochondrial pathway. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Moreover, we showed that the downregulation of FoxM1 enhanced cisplatin-induced A549/CDDP cell apoptosis through the activation of the c-Jun NH2-terminal kinase (JNK)/mitochondrial pathway. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |