Title : KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity.

Pub. Date : 2015 Jan 7

PMID : 25563361






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 KUD773 induced an increase of Cdk1 phosphorylation at Thr(161) (a stimulatory phosphorylation site) and a decrease of phosphorylation at Tyr(15) (an inhibitory phosphorylation site), suggesting the activation of Cdk1. Threonine cyclin dependent kinase 1 Homo sapiens