Title : Modulation of the iodination reaction in normal human neutrophils and in whole blood by penicillamine, congeners and intracellular enzyme catalase and superoxide dismutase.

Pub. Date : 1989 Jul-Aug

PMID : 2556228






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We have demonstrated that penicillamine (PSH) has the capacity to effect phagocytic cells by its interaction with the myeloperoxidase-halide system (MPOHS). halide myeloperoxidase Homo sapiens
2 In conclusion, PSH inhibits the myeloperoxidase-halide system at a cellular level by scavenging H2O2 rather than by oxidation of the myeloperoxidase enzyme. halide myeloperoxidase Homo sapiens