Pub. Date : 2015 Jan
PMID : 25559956
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Immunohistochemical staining and Western blotting showed that RAPA treatment significantly down-regulated the enhanced levels of TGF-beta1 and alpha-SMA in lung tissues caused by PQ exposure. | Paraquat | transforming growth factor, beta 1 | Mus musculus |
| 2 | CONCLUSIONS: This study demonstrates that RAPA treatment effectively suppresses PQ-induced alveolar collapse and collagen deposition in lung tissues through reducing the expression of TGF-beta1 and alpha-SMA. | Paraquat | transforming growth factor, beta 1 | Mus musculus |