Title : 22-S-Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXRα.

Pub. Date : 2015 Apr

PMID : 25557254






2 Functional Relationships(s)
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1 22-S-Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXRalpha. Ethanol C-C motif chemokine ligand 2 Homo sapiens
2 Here, we show the role of liver X receptor alpha (LXRalpha) in the regulation of MCP-1 expression during the development of ethanol-induced fatty liver injury, using an antagonist, 22-S-hydroxycholesterol (22-S-HC). Ethanol C-C motif chemokine ligand 2 Homo sapiens