Title : β-elemene induces caspase-dependent apoptosis in human glioma cells in vitro through the upregulation of Bax and Fas/ FasL and downregulation of Bcl-2.

Pub. Date : 2014

PMID : 25556484






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Real-time quantitative PCR and Western-blotting assay were performed to investigated the influence of beta-elemene on expression levels of Fas/FasL, caspase-3, Bcl-2 and Bax. beta-elemene caspase 3 Homo sapiens
2 Activation of caspase-3,-8 and -9 was increased and the pro-apoptotic factors Fas/FasL and Bax were upregulated, while the anti-apoptotic Bcl-2 was downregulated after treatment with beta-elemene at both mRNA and protein levels. beta-elemene caspase 3 Homo sapiens