Title : Tissue plasminogen activator and plasmin independently decrease human neutrophil activation.

Pub. Date : 1989

PMID : 2555642






2 Functional Relationships(s)
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1 t-PA (1 to 100 micrograms/ml) decreased f-MLP-induced chemotaxis and ionophore A23187-induced superoxide and LTB4 release in isolated neutrophils, and these effects were not blocked by the plasmin-inhibitor epsilon-aminocaproic acid (epsilon-ACA). Aminocaproic Acid plasminogen activator, tissue type Homo sapiens
2 t-PA (1 to 100 micrograms/ml) decreased f-MLP-induced chemotaxis and ionophore A23187-induced superoxide and LTB4 release in isolated neutrophils, and these effects were not blocked by the plasmin-inhibitor epsilon-aminocaproic acid (epsilon-ACA). Aminocaproic Acid plasminogen activator, tissue type Homo sapiens